Thanks for taking the time to provide more details, CRM. It's a refreshing change compared to the hit and run researches we've seen in the the past. So I wish you well with it. If I was within you age bracket, and wasn't to go on record I'd probably give you my take on it. As i'm not your typical cannabis consumer.. I started out like most, recreationally, off and on over the years. Until my father passed on from cancer, only then i started to look at the medicinal side of cannabis. Years previously, I too did intially believe the medicinal side was a joke until his passing. After he passed, i became a member here at OSA which really opened my eyes to all things cannabis. Anyway, nearly 15 years have past since then and I myself have been my own guinea pig, growing and testing strains for pain management. It's not a exact science but i've got my own management plan with it that keeps me off the opiates. I've found quite a few hybrid strains around 60/40% sativa and indica crosses work fairly well with me, even the 50/50 hybrids have been quite suffice as well. But anyway, contrary to what most believe. It's not a case of consuming as much you can. But moreso a case of micro-dosing throughout the day. Traditionally, i was a old school smoker that was into the sativa's primarily. But what i'm finding the hybrids are proving to be more beneficial. As i said it's not a exact science, i'm guessing the indica side of it is dealing with the medicinal area, and the sativa is providing the uplifting element that allows me to get on with my daily commitments. That said, utilising cannabis medicinally is no different to what we're finding with pharmaceutical meds (imo). Whereas, what works with one client, may not work for another. So this being the case it seems it's going to be trial and error with many until they find strains/hybrids that works for them (or until proper unlimited/unbiased studies can be carried out and narrowed down to certain ailment/s) if they so happen to take this route. Regardless, all the best with it, CRM.